| Name | Class | C. | Type | Icons | Traits | Set | Encounter |
|---|---|---|---|---|---|---|---|
| .18 Derringer | Survivor | 3 | Asset. Hand | Item. Weapon. Firearm. Illicit. | Stella Clark 5 | ||
| .32 Colt | Guardian | 3 | Asset. Hand | Item. Weapon. Firearm. | The Path to Carcosa 20 | ||
| .35 Winchester | Guardian | 4 | Asset. Hand x2 | Item. Weapon. Firearm. | Dark Side of the Moon 195 | ||
| .45 Automatic | Guardian | 4 | Asset. Hand | Item. Weapon. Firearm. | Core Set 16 | ||
| .45 Automatic | Guardian | 4 | Asset. Hand | Item. Weapon. Firearm. | Revised Core Set 16 | ||
| .45 Thompson | 6 | Asset. Hand x2 | Item. Weapon. Firearm. Illicit. | The Secret Name 115 | |||
| "Catch!" | Survivor | 0 | Event | Tactic. Trick. | The Drowned City Investigator Expansion 86 | ||
| "Do as I do." | Seeker | 0 | Event | Insight. | Keith's Custom Player Cards 43 | ||
| "Eat lead!" | Guardian | 1 | Event | Tactic. | Return to the Path to Carcosa 2 | ||
| "Fool me once..." (1) | Guardian | 1 | Event | Insight. Tactic. | A Thousand Shapes of Horror 156 | ||
| "Get behind me!" | Guardian | 0 | Event | Spirit. Tactic. | Edge of the Earth Investigator Expansion 21 | ||
| "Get over here!" | Guardian | 2 | Event | Spirit. Tactic. | Nathaniel Cho 14 | ||
| "Hit me!" | 1 | Event | Fortune. Gambit. | Edge of the Earth Investigator Expansion 112 | |||
| "I'll see you in hell!" | Guardian | 0 | Event | Spirit. | A Phantom of Truth 189 | ||
| "I've got a plan!" | Seeker | 3 | Event | Insight. Tactic. | The Miskatonic Museum 107 | ||
| "I've got a plan!" (2) | Seeker | 2 | Event | Insight. Tactic. | Harvey Walters 25 | ||
| "If it bleeds..." | Guardian | 1 | Event | Undimensioned and Unseen 225 | |||
| "Let me handle this!" | Guardian | 0 | Event | Spirit. | The Path to Carcosa 22 | ||
| "Look what I found!" | Survivor | 2 | Event | Fortune. | Core Set 79 | ||
| "Look what I found!" | Survivor | 2 | Event | Fortune. | Revised Core Set 79 | ||
| "Look what I found!" | Survivor | 2 | Event | Fortune. | Core Set (2026) 78 | ||
| "Look what I found!" | Survivor | 2 | Event | Fortune. | Stella Clark 17 | ||
| "Make 'em sing" | Guardian | 2 | Event | Tactic. | Tommy Muldoon 10 | ||
| "Not without a fight!" | Survivor | Skill | Innate. | Black Stars Rise 272 | |||
| "Shove off!" | Survivor | 1 | Event | Tactic. | Core Set (2026) 79 | ||
| "Throw the Book at Them!" | Seeker | 1 | Event | Gambit. Improvised. | The Feast of Hemlock Vale Investigator Expansion 49 | ||
| (Deprecated) Cover Retreat | Seeker | 0 | Event | Assistance. Favor. | Keith's Custom Other Cards 148 | ||
| (Deprecated) Distraction | Seeker | 0 | Event | Assistance. Favor. | Keith's Custom Other Cards 146 | ||
| A Chance Encounter | Survivor | 1 | Event | Fortune. | Where Doom Awaits 270 | ||
| A Glimmer of Hope | Survivor | 1 | Event | Blessed. Fortune. | Point of No Return 245 | ||
| A Test of Will (1) | Survivor | 1 | Event | Spirit. | The Unspeakable Oath 156 | ||
| A Test of Will | Survivor | 1 | Event | Spirit. | Stella Clark 13 | ||
| Abductive Reasoning (1) | Survivor | Skill | Innate. Practiced. | Monogatari Player Cards 76 | |||
| Able Bodied | Survivor | Skill | Innate. | The Circle Undone 38 | |||
| Absolute Focus | Guardian | Skill | Practiced. | Keith's Custom Player Cards 31 | |||
| Absolution | Guardian | -2 | Event | Spell. Blessed. | The Feast of Hemlock Vale Investigator Expansion 24 | ||
| Ace of Rods: The Fateful Step (1) | Neutral | 3 | Asset. Tarot | Tarot. | The Circle Undone 40 | ||
| Ace of Swords: Let Your Arrow Fly True (1) | Guardian | 3 | Asset. Tarot | Tarot. | The Circle Undone 23 | ||
| Act of Desperation | Survivor | 0 | Event | Tactic. Gambit. | The Circle Undone 37 | ||
| Adapt and Overcome | Guardian | Skill | Practiced. | Tommy Muldoon 17 | |||
| Alchemical Distillation | Seeker | 2 | Asset. Hand | Item. Science. | The Scarlet Keys Investigator Expansion 40 | ||
| Aleksey Saburov: Always on the Mend | Survivor | 3 | Asset. Ally | Ally. | Core Set (2026) 72 | ||
| Alice Luxley: Fearless Flatfoot | Guardian | 4 | Asset. Ally | Ally. Detective. Police. | The Wages of Sin 151 | ||
| Alter Fate (1) | Survivor | 3 | Event | Spell. Blessed. | Return to the Forgotten Age 9 | ||
| Alton O'Connell: Ghost Hunter | Seeker | 3 | Asset. Ally | Ally. Detective. Reporter. | The Drowned City Investigator Expansion 33 | ||
| Ambush (1) | Guardian | 2 | Event | Tactic. | The Unspeakable Oath 148 | ||
| Analysis | Seeker | Skill | Practiced. | The Scarlet Keys Investigator Expansion 49 | |||
| Anamnesis | Guardian | 1 | Event | Insight. Spirit. | Monogatari Player Cards 22 | ||
| Anatomical Diagrams | Seeker | 1 | Event | Insight. | Echoes of the Past 108 | ||
| Ancestral Knowledge (3) | Seeker | Asset | Talent. | Into the Maelstrom 303 | |||
| Ancestral Token | Guardian | 3 | Asset. Accessory | Item. Charm. Blessed. | The Feast of Hemlock Vale Investigator Expansion 19 | ||
| Anchor Chain | Survivor | 3 | Asset. Hand | Item. Tool. | The Drowned City Investigator Expansion 81 | ||
| Ancient Stone: Unidentified (1) | Seeker | 1 | Asset. Hand | Item. Relic. | The Forgotten Age 22 | ||
| Anna Kaslow: Mysterious Soothsayer (4) | Neutral | 3 | Asset. Ally | Ally. Clairvoyant. | In the Clutches of Chaos 283 | ||
| Antiquary (3) | 3 | Asset | Talent. | Edge of the Earth Investigator Expansion 124 | |||
| Aquinnah: The Forgotten Daughter (1) | Survivor | 5 | Asset. Ally | Ally. | Core Set 82 | ||
| Aquinnah: The Forgotten Daughter (1) | Survivor | 5 | Asset. Ally | Ally. | Revised Core Set 82 | ||
| Arcane Enlightenment | Seeker | 2 | Asset. Arcane | Ritual. | Harvey Walters 5 | ||
| Archaic Glyphs: Untranslated | Seeker | 0 | Asset. Hand | Item. Occult. Tome. | The Path to Carcosa 25 | ||
| Archaic Glyphs: Guiding Stones (3) | Seeker | 2 | Asset. Arcane | Spell. | A Phantom of Truth 192 | ||
| Archaic Glyphs: Prophecy Foretold (3) | Seeker | 2 | Asset. Arcane | Spell. | A Phantom of Truth 193 | ||
| Archaic Glyphs: Markings of Isis (3) | Seeker | 2 | Asset. Arcane | Spell. | Return to the Path to Carcosa 4 | ||
| Archibald MacVeigh: Beleaguered Lecturer (5) | Neutral | 4 | Asset. Ally | Ally. | The Drowned City Investigator Expansion 117 | ||
| Archive of Conduits: Unidentified | Seeker | 2 | Asset. Hand | Item. Tome. Occult. | Edge of the Earth Investigator Expansion 33 | ||
| Ariadne's Twine (3) | Seeker | 0 | Asset. Arcane | Ritual. | Into the Maelstrom 304 | ||
| Armed to the Teeth | Guardian | Skill | Practiced. | Tommy Muldoon 18 | |||
| Art Student | Seeker | 2 | Asset. Ally | Ally. Miskatonic. | The Essex County Express 149 | ||
| Artistic Inspiration | Seeker | 2 | Asset | Talent. | The Drowned City Investigator Expansion 34 | ||
| Ascetic | Neutral | Asset | Condition. | The Drowned City Investigator Expansion 95 | |||
| Assemble the Team | Guardian | 1 | Event | Spirit. | Keith's Custom Player Cards 25 | ||
| Astounding Revelation | Seeker | Event | Research. | The Dream-Eaters 23 | |||
| At a Crossroads (1) | Survivor | Event | Dilemma. Insight. | The Scarlet Keys Investigator Expansion 109 | |||
| Autopsy Report (3) | Seeker | 3 | Asset. Hand | Item. Tome. Science. | Carolyn Fern 26 | ||
| Back Alley Surgeon | Seeker | 1 | Asset | Acquaintance. Science. Doctor? | Keith's Custom Player Cards 127 | ||
| Backpack | Neutral | 2 | Asset. Body | Item. | The Forgotten Age 37 | ||
| Backpack (2) | Neutral | 1 | Asset. Body | Item. | Return to the Forgotten Age 11 | ||
| Bait and Switch | Survivor | 1 | Event | Trick. | The Dunwich Legacy 34 | ||
| Bandages | Survivor | 2 | Asset | Item. | Edge of the Earth Investigator Expansion 73 | ||
| Bandages | Survivor | 2 | Asset | Item. | Core Set (2026) 73 | ||
| Bandolier | Guardian | 2 | Asset. Body | Item. | The Essex County Express 147 | ||
| Bangle of Jinxes (1) | Survivor | 2 | Asset. Accessory | Item. Charm. Cursed. | Edge of the Earth Investigator Expansion 75 | ||
| Barricade | Seeker | 0 | Event | Insight. Tactic. | Core Set 38 | ||
| Barricade | Seeker | 0 | Event | Insight. Tactic. | Revised Core Set 38 | ||
| Barricade (3) | Seeker | 0 | Event | Insight. Tactic. | Return to the Night of the Zealot 4 | ||
| Baseball Bat | Survivor | 2 | Asset. Hand x2 | Item. Weapon. Melee. | Core Set 74 | ||
| Baseball Bat | Survivor | 2 | Asset. Hand x2 | Item. Weapon. Melee. | Revised Core Set 74 | ||
| Beat Cop | Guardian | 4 | Asset. Ally | Ally. Police. | Core Set 18 | ||
| Beat Cop | Guardian | 4 | Asset. Ally | Ally. Police. | Revised Core Set 18 | ||
| Belly of the Beast | Survivor | 1 | Event | Gambit. Trick. | The Wages of Sin 160 | ||
| Beloved | Survivor | Skill | Innate. Blessed. | The Innsmouth Conspiracy 36 | |||
| Beseeching Prayer | Guardian | 2 | Asset. Arcane | Ritual. Blessed. | Keith's Custom Player Cards 26 | ||
| Bide Your Time | Neutral | 0 | Event | Double. | The Feast of Hemlock Vale Investigator Expansion 129 | ||
| Bizarre Diagnosis | Seeker | 0 | Event | Insight. Science. | The Scarlet Keys Investigator Expansion 46 | ||
| Blackjack | Guardian | 1 | Asset. Hand | Item. Weapon. Melee. | The Dunwich Legacy 16 | ||
| Blasphemous Covenant (2) | Seeker | Asset | Covenant. Cursed. | In Too Deep 113 | |||
| Blessed Blade | Guardian | 3 | Asset. Hand | Item. Weapon. Melee. Blessed. | The Innsmouth Conspiracy 18 | ||
| Blood Eclipse (1) | Guardian | 1 | Event | Spell. Spirit. | Return to the Forgotten Age 1 | ||
| Blood of K'n-yan (3) | Neutral | 2 | Event | Spell. | The Drowned City Investigator Expansion 114 | ||
| Bloody Lab Coat | Seeker | 2 | Asset. Body | Item. Clothing. | Keith's Custom Player Cards 42 | ||
| Bodyguard | Guardian | 3 | Asset. Ally | Ally. | Core Set (2026) 16 | ||
| Bolas | Guardian | 1 | Event | Tactic. | The Scarlet Keys Investigator Expansion 25 | ||
| Book of Psalms | Guardian | 3 | Asset. Hand | Item. Tome. Blessed. | The Innsmouth Conspiracy 17 | ||
| Book of Warding | Seeker | 3 | Asset. Hand | Item, Tome. | Monogatari Player Cards 33 | ||
| Bookkeeping (3) | Seeker | 1 | Event | Insight. | Keith's Custom Player Cards 55 | ||
| Bound for the Horizon (2) | Neutral | 2 | Asset | Talent. | The Drowned City Investigator Expansion 102 | ||
| Bounty | Guardian | 0 | Event | Fortune. | Tommy Muldoon 11 | ||
| Boxing Gloves | Guardian | 3 | Asset. Hand x2 | Item. Weapon. | Nathaniel Cho 5 | ||
| Brand of Cthugha (1) | 2 | Asset. Arcane | Spell. | Edge of the Earth Investigator Expansion 90 | |||
| Breach the Door | Guardian | 2 | Event | Insight. Tactic. Police. | The Scarlet Keys Investigator Expansion 26 | ||
| Breaking your Limits (5) | Neutral | 0 | Event | Spirit. Transcendent. | Keith's Custom Player Cards 120 | ||
| Broken Bottle | Neutral | 1 | Asset. Hand | Item. Weapon. Melee. Improvised. | Core Set (2026) 86 | ||
| Broken Diadem: Crown of Dying Light (5) | Neutral | 1 | Asset | Item. Charm. Mask. | The Feast of Hemlock Vale Investigator Expansion 133 | ||
| Brother Xavier: Pure of Spirit (1) | Guardian | 5 | Asset. Ally | Ally. | The Miskatonic Museum 106 | ||
| Brute Force (1) | Survivor | Skill | Innate. Developed. | A Thousand Shapes of Horror 166 | |||
| Brute Force | Survivor | Skill | Innate. | Keith's Custom Player Cards 136 | |||
| Bulletproof Vest (3) | Neutral | 2 | Asset. Body | Item. Armor. | Core Set 94 | ||
| Bulletproof Vest (3) | Neutral | 2 | Asset. Body | Item. Armor. | Revised Core Set 94 | ||
| Burn After Reading (1) | Survivor | 1 | Event | Insight. | Edge of the Earth Investigator Expansion 76 | ||
| Burning the Midnight Oil | Seeker | 0 | Event | Insight. | Harvey Walters 14 | ||
| Butterfly Effect (1) | Survivor | 0 | Event | Paradox. Blessed. Cursed. | Devil Reef 160 | ||
| Call for Backup (2) | Neutral | 1 | Event | Favor. Synergy. | Edge of the Earth Investigator Expansion 129 | ||
| Calling in Favors | Neutral | 1 | Event | Favor. | The Unspeakable Oath 158 | ||
| Calm the Nerves | Neutral | 1 | Event | Spirit. | Keith's Custom Player Cards 109 | ||
| Captivating Discovery | Seeker | 1 | Event | Insight. | The Scarlet Keys Investigator Expansion 47 | ||
| Captivating Performance (3) | Neutral | 3 | Asset | Ritual. | The Drowned City Investigator Expansion 108 | ||
| Caustic Reaction | Seeker | 2 | Event | Tactic. Science. | Carolyn Fern 11 | ||
| Caustic Reaction (2) | Seeker | 2 | Event | Tactic. Science. | Carolyn Fern 23 | ||
| Cautious | Survivor | 1 | Asset | Talent. | Keith's Custom Player Cards 125 | ||
| Celaeno Fragments: Book of Books | Seeker | 1 | Asset. Hand | Item. Tome. | Harvey Walters 6 | ||
| Charisma (3) | Neutral | Asset | Talent. | Revised Core Set 194 | |||
| Charisma (3) | Neutral | Asset | Talent. | The Essex County Express 158 | |||
| Charisma (3) | Neutral | Asset | Talent. | Core Set (2026) 95 | |||
| Charles Ross, Esq.: Acquisitions and Solicitation | Seeker | 2 | Asset. Ally | Ally. Patron. | The Unspeakable Oath 149 | ||
| Chemistry Set | Seeker | 2 | Asset. Accessory | Item. Tool. Science. | The Feast of Hemlock Vale Investigator Expansion 40 | ||
| Cherished Keepsake | Survivor | 0 | Asset. Accessory | Item. Charm. | Echoes of the Past 114 | ||
| Cherished Keepsake (1) | Survivor | 0 | Asset. Accessory | Item. Charm. | Stella Clark 20 | ||
| Chronicon Eternum: Unidentified | Seeker | 1 | Asset. Hand | Item. Relic. Tome. | Keith's Custom Player Cards 157 | ||
| Circlet of Sealing (1) | Neutral | 2 | Asset. Accessory | Item. Relic. | Keith's Custom Player Cards 111 | ||
| Clean Them Out | Guardian | 0 | Event | Spirit. Tactic. | Nathaniel Cho 11 | ||
| Cleaning Kit | Guardian | 3 | Asset. Accessory | Item. Tool. | The Feast of Hemlock Vale Investigator Expansion 20 | ||
| Close Quarters | Guardian | 2 | Event | Spirit. Tactic. | Keith's Custom Player Cards 28 | ||
| Combat Training (1) | Guardian | 1 | Asset | Talent. Composure. | Echoes of the Past 107 | ||
| Confidence | Neutral | Skill | Innate. | The Drowned City Investigator Expansion 97 | |||
| Confound (3) | Seeker | 2 | Event | Insight. Trick. | The Feast of Hemlock Vale Investigator Expansion 57 | ||
| Conjure Weapon | Guardian | 2 | Event | Spell. Spirit. | Monogatari Player Cards 23 | ||
| Connect the Dots | Seeker | 4 | Event | Insight. | The Circle Undone 25 | ||
| Contemplation | Survivor | 1 | Event | Introspection. | Monogatari Player Cards 72 | ||
| Contemplative | Survivor | Skill | Innate. | The Drowned City Investigator Expansion 88 | |||
| Control Variable | Seeker | 1 | Event | Insight. Science. Cursed. | The Feast of Hemlock Vale Investigator Expansion 46 | ||
| Correlate All Its Contents | Seeker | 1 | Event | Insight. | The Drowned City Investigator Expansion 40 | ||
| Cosmic Revelation (1) | Seeker | 0 | Event | Insight. Spell. | The Drowned City Investigator Expansion 41 | ||
| Counterattack (1) | Guardian | 1 | Event | Spirit. Tactic. | Core Set (2026) 26 | ||
| Counterpunch | Guardian | 0 | Event | Spirit. Tactic. | Nathaniel Cho 12 | ||
| Cowl of Sekhmet: Cloak of the Pharaohs (3) | Neutral | 2 | Asset. Body | Item. Clothing. Relic. | The Drowned City Investigator Expansion 109 | ||
| Crack the Case | Seeker | 0 | Event | Insight. | The Secret Name 110 | ||
| Crafty (3) | 3 | Asset | Talent. | Edge of the Earth Investigator Expansion 123 | |||
| Crowbar | Guardian | 3 | Asset. Hand | Item. Weapon. Tool. Melee. | The Drowned City Investigator Expansion 21 | ||
| Cryptic Grimoire: Untranslated | Seeker | 3 | Asset. Hand | Item. Tome. Occult. | The Innsmouth Conspiracy 22 | ||
| Cryptic Writings | Seeker | 0 | Event | Insight. | Harvey Walters 15 | ||
| Cryptic Writings (2) | Seeker | 0 | Event | Insight. | Harvey Walters 24 | ||
| Cryptographic Cipher | Seeker | 3 | Asset. Hand | Item. Tool. | The Innsmouth Conspiracy 21 | ||
| Cunning Distraction | Survivor | 5 | Event | Tactic. | Core Set 78 | ||
| Cunning Distraction | Survivor | 5 | Event | Tactic. | Revised Core Set 78 | ||
| Curiosity | Seeker | Skill | Innate. | The Circle Undone 26 | |||
| Custom Grip | Guardian | 1 | Event | Upgrade. | Tommy Muldoon 12 | ||
| Custom Modifications | Guardian | 3 | Event | Upgrade. Supply. | The Scarlet Keys Investigator Expansion 23 | ||
| Dakota Garofalo: On the Hunt (3) | Neutral | 4 | Asset. Ally | Ally. Hunter. Wayfarer. | The Drowned City Investigator Expansion 110 | ||
| Daniel Jameson: Seasoned Hunter | Survivor | 3 | Asset. Ally | Ally. Hunter. | Miguel de la Cruz 5 | ||
| Daring | Guardian | Skill | Innate. | The Search for Kadath 111 | |||
| Dark Horse | Survivor | 3 | Asset | Condition. | Undimensioned and Unseen 234 | ||
| Dauntless Spirit (1) | Survivor | Skill | Innate. Developed. | Edge of the Earth Investigator Expansion 78 | |||
| Dave Reacher: The Collector | Seeker | 4 | Asset. Ally | Ally. Patron. | Keith's Custom Player Cards 41 | ||
| Dawn Star (1) | Neutral | 1 | Event | Ritual. Blessed. | The Feast of Hemlock Vale Investigator Expansion 131 | ||
| De-Escalate | Seeker | 1 | Event | Insight. | Carolyn Fern 15 | ||
| Death • XIII: Free from the Past (1) | Seeker | 3 | Asset. Tarot | Tarot. | The Circle Undone 27 | ||
| Decoy Trap | Survivor | 2 | Event | Trap. Trick. | Miguel de la Cruz 12 | ||
| Deduction | Seeker | Skill | Practiced. | Core Set 39 | |||
| Deduction | Seeker | Skill | Practiced. | Revised Core Set 39 | |||
| Deduction (2) | Seeker | Skill | Practiced. Expert. | The Essex County Express 150 | |||
| Deduction | Seeker | Skill | Practiced. | Core Set (2026) 39 | |||
| Deduction | Seeker | Skill | Practiced. | Harvey Walters 19 | |||
| Deduction | Seeker | Skill | Practiced. | Carolyn Fern 17 | |||
| Deduction (2) | Seeker | Skill | Practiced. Expert. | Carolyn Fern 25 | |||
| Deep Knowledge | Seeker | 0 | Event | Insight. Cursed. | The Innsmouth Conspiracy 23 | ||
| Defensive Stance (1) | Guardian | Skill | Practiced. Expert. | Edge of the Earth Investigator Expansion 24 | |||
| Delay the Inevitable | Guardian | 2 | Event | Insight. Spirit. Tactic. | The Circle Undone 21 | ||
| Desperate Search | Neutral | Skill | Desperate. | Echoes of the Past 117 | |||
| Devil's Luck (1) | Survivor | 1 | Event | Fortune. | The Unspeakable Oath 157 | ||
| Dial of Ancients: Unidentified | Seeker | 3 | Asset. Accessory | Item. Relic. Cursed. | The Drowned City Investigator Expansion 35 | ||
| Dig Deep | Survivor | 2 | Asset | Talent. | Core Set 77 | ||
| Dig Deep | Survivor | 2 | Asset | Talent. | Revised Core Set 77 | ||
| Dimensional Vortex (5) | Neutral | 2 | Event | Spell. | The Drowned City Investigator Expansion 124 | ||
| Disc of Itzamna: Protective Amulet (2) | Seeker | 3 | Asset. Accessory | Item. Relic. | Core Set 41 | ||
| Disc of Itzamna: Protective Amulet (2) | Seeker | 3 | Asset. Accessory | Item. Relic. | Revised Core Set 41 | ||
| Disc of Itzamna: Protective Amulet | Seeker | 3 | Asset. Accessory | Item. Relic. | Harvey Walters 7 | ||
| Discarded Dog Tags | Guardian | 2 | Asset. Accessory | Item. Charm. | Keith's Custom Player Cards 27 | ||
| Dissection Tools | Seeker | 2 | Asset. Hand | Item. Tool. Science. | The Scarlet Keys Investigator Expansion 43 | ||
| Distribute Supplies | Guardian | 0 | Event | Tactic. Supply. | Keith's Custom Player Cards 29 | ||
| Divination (1) | 3 | Asset. Arcane | Spell. Augury. | Edge of the Earth Investigator Expansion 101 | |||
| Do-or-Die | Survivor | Skill | Fortune. | Miguel de la Cruz 18 | |||
| Dodge | Guardian | 1 | Event | Tactic. | Core Set 23 | ||
| Dodge | Guardian | 1 | Event | Tactic. | Revised Core Set 23 | ||
| Dodge | Guardian | 1 | Event | Tactic. | Nathaniel Cho 13 | ||
| Dorothy Simmons: Straight-A Student | Seeker | 3 | Asset. Ally | Ally. Miskatonic. | Core Set (2026) 30 | ||
| Double Down (2) | Neutral | Skill | Innate. | The Drowned City Investigator Expansion 107 | |||
| Dr. Charles West III: Knows His Purpose | Seeker | 3 | Asset. Ally | Ally. Science. | The Feast of Hemlock Vale Investigator Expansion 41 | ||
| Dr. Elli Horowitz: Assistant Curator | Seeker | 3 | Asset. Ally | Ally. Assistant. | The Forgotten Age 21 | ||
| Dr. Milan Christopher: Professor of Entomology | Seeker | 4 | Asset. Ally | Ally. Miskatonic. | Core Set 33 | ||
| Dr. Milan Christopher: Professor of Entomology | Seeker | 4 | Asset. Ally | Ally. Miskatonic. | Revised Core Set 33 | ||
| Dr. William T. Maleson: Working on Something Big | Seeker | 1 | Asset. Ally | Ally. Miskatonic. | Lost in Time and Space 302 | ||
| Dr. William T. Maleson: Working on Something Bigger (2) | Seeker | 1 | Asset. Ally | Ally. Miskatonic. | The Scarlet Keys Investigator Expansion 54 | ||
| Drawing Thin | Survivor | 0 | Asset | Talent. | The Wages of Sin 159 | ||
| Dream Diary: Untranslated | Seeker | 2 | Asset. Hand | Item. Tome. Charm. | The Search for Kadath 112 | ||
| Dream Diary: Dreams of an Explorer (3) | Seeker | 2 | Asset. Hand | Item. Tome. Charm. | Point of No Return 236 | ||
| Dream Diary: Dreams of a Madman (3) | Seeker | 2 | Asset. Hand | Item. Tome. Charm. | Point of No Return 237 | ||
| Dream Diary: Dreams of a Child (3) | Seeker | 2 | Asset. Hand | Item. Tome. Charm. | Point of No Return 238 | ||
| Dream-Enhancing Serum | Seeker | 3 | Asset. Arcane | Item. Science. | A Thousand Shapes of Horror 159 | ||
| Dreamer's Chronicle | Seeker | 4 | Asset. Hand | Item. Tome. | Carolyn Fern 5 | ||
| Dreams of the Clay (1) | Neutral | Skill | Innate. Augury. | The Drowned City Investigator Expansion 100 | |||
| Dumb Luck | Survivor | 2 | Event | Fortune. | The Forgotten Age 34 | ||
| Dumb Luck | Survivor | 2 | Event | Fortune. | Stella Clark 14 | ||
| Dynamite Blast | Guardian | 5 | Event | Tactic. | Core Set 24 | ||
| Dynamite Blast | Guardian | 5 | Event | Tactic. | Revised Core Set 24 | ||
| Earthly Serenity (1) | 2 | Asset. Arcane | Spell. | Edge of the Earth Investigator Expansion 117 | |||
| Eidetic Memory (3) | Seeker | Event | Spirit. | Dim Carcosa 306 | |||
| Elaborate Distraction | Survivor | 3 | Event | Trick. Double. | The Feast of Hemlock Vale Investigator Expansion 112 | ||
| Elder Sign Amulet (3) | Neutral | 2 | Asset. Accessory | Item. Relic. | Core Set 95 | ||
| Elder Sign Amulet (3) | Neutral | 2 | Asset. Accessory | Item. Relic. | Revised Core Set 95 | ||
| Eldritch Research | Seeker | 1 | Event | Insight. | Keith's Custom Player Cards 44 | ||
| Eldritch Sophist | Seeker | 4 | Asset. Ally | Ally. Miskatonic. | In Too Deep 111 | ||
| Eldritch Tongue | Neutral | 2 | Asset. Arcane | Ritual. | The Feast of Hemlock Vale Investigator Expansion 128 | ||
| Emergency Aid | Guardian | 2 | Event | Insight. Science. | The Miskatonic Museum 105 | ||
| Emergency Cache | Neutral | 0 | Event | Supply. | Core Set 88 | ||
| Emergency Cache | Neutral | 0 | Event | Supply. | Revised Core Set 88 | ||
| Emergency Cache (2) | Neutral | 0 | Event | Supply. | Revised Core Set 193 | ||
| Emergency Cache (2) | Neutral | 0 | Event | Supply. | Blood on the Altar 194 | ||
| Emergency Cache (3) | Neutral | 0 | Event | Supply. | The Pallid Mask 239 | ||
| Emergency Cache | Neutral | 0 | Event | Supply. | Core Set (2026) 89 | ||
| Empirical Hypothesis | Seeker | 2 | Asset | Talent. Science. | The Scarlet Keys Investigator Expansion 41 | ||
| Enchanted Blade | 3 | Asset. Hand. Arcane | Item. Relic. Weapon. Melee. | The Secret Name 118 |